Best Warren Buffett Companies To Watch For 2015

Best Warren Buffett Companies To Watch For 2015: Immune Design Corp (IMDZ)

Immune Design Corp, incorporated on February 20, 2008, is a clinical-stage immunotherapy company. The Company has engineered its technologies to activate the immune systems natural ability to create tumor-specific cytotoxic T cells (CTLs), to fight cancer. The Company is developing multiple product candidates from its two discovery platforms, DCVex and GLAAS. The Companys product candidates, LV305, CMB305 and G100, utilize multiple immuno-oncology approaches. LV305 was developed from the DCVex platform and it is enrolling patients in a Phase I clinical trial for the treatment of five solid tumor types. CMB305 is a prime-boost approach that combines LV305 with a second agent, G305. G100 was developed from the GLAAS platform and it is enrolling patients with Merkel cell carcinoma in a Phase I clinical trial.

The Companys immuno-oncology product candidates are being developed in two separate approaches: Specific Antigen and Endogenous Antigen. The Specif ic Antigen approach uses selected antigens that are also present in the patients tumor so that the immune system will be educated to recognize the tumor antigen and kill tumor cells expressing the antigen. The Endogenous Antigen approach, in contrast, does not require a selected antigen present in the tumor. It instead relies on treatments, such as chemotherapy or local radiation to lyse tumors and release endogenous antigens, which are then captured by neighboring GLAAS-activated dendritic cells, generating a varied immune response. The Company utilizes DCVex and GLAAS to develop product candidates that work in vivo and are designed to create and expand diverse armies of CTLs to fight tumors. DCVex is a discovery platform that uses a first-in-class vector to generate product candidates designed to create CTLs in vivo. The DCVex vector is a delivery system based on a re-engineered virus to carry the genetic information of a tumor antigen safely and selectiv! ely to dendriti c cells (DCs), in the skin. The GLAAS platform also works in vivo and is based on a small synthetic molecule called GLA, which stands for glucopyranosyl lipid A. GLA selectively binds to the TLR4 receptor and causes potent activation of the DC.

Advisors' Opinion:

• [By WWW.DAILYFINANCE.COM]

  www.gopro.com Now that it's nearly over, we can definitively say that 2014 has been one of the best years for initial public stock offerings in history. In terms of proceeds raised from IPOs, 2014 will challenge or even exceed the year 2000. Which is saying something: That was the height of the dot.com frenzy, when seemingly every new company with a website felt compelled to list on the stock exchange. As can be expected of a busy IPO year, some of 2014's new stock market titles have been runaway hits soaring above their issue price, while others have belly-flopped. Since we're heading into the most optimistic time of the year, we'll shine a light on the three best performers. In order of stock price appreciation, they are: GoPro (GPRO) 2014's current IPO front-runner is this company, maker of the popular action photography camera -- the one that's usually responsible for those hairy point-of-view videos posted on Facebook (FB) and other online sharing sites. GoPro's stock hit the market at the end of June priced at $24, and as if this writing it now stands at $70.72 for a muscular 195 percent total return. Although that's impressive, it should be noted that the current price is quite a bit lower than the stock's high of nearly $94, which it touched in early October. But then the camera was effectively blamed for the horrific accident that befell Formula One racing star Michael Schumacher -- although the journalist making the allegation later recanted -- and the shares cratered. The stock recovered after the company reported strong third-quarter earnings, and all seemed well again... until GoPro decided to float a secondary issue of stock. It'll sell 10.3 million f! resh shar! es on the market, adding to the nearly 126 million currently outstanding. When secondary share issues are announced, a company's stock often takes a hit, since investors aren't too crazy about their existing stakes being diluted. Regardless, on a fundamental basis GoPro is a popular, if

source from Top Stocks To Buy For 2015:http://www.topstocksforum.com/best-warren-buffett-companies-to-watch-for-2015-2.html